What is CBDP, where did it come from and what are its effects?
- What is CBDP and what is its chemical structure?
- How is it made?
- What are the effects of CBDP?
- Possible side effects
- Conclusion
What is CBDP and what is its chemical structure?
CBDP, or cannabidiophorol, also CBD-C7 and CBD-heptyl, is a phytocannabinoid discovered naturally in the cannabis plant by Italian scientists in 2019. It had previously been identified as a synthetic compound.
Cannabidiol is the heptyl homologue of cannabidiol, or CBD. The term homologue refers to compounds that share similar structure and properties but differ in a specific repeating element or group of atoms. In this context, 'heptyl' denotes the difference between CBD and CBDP, which is that CBDP has a longer side chain. CBDP has a 7-membered side chain, whereas CBD has a 5-membered alkyl chain. The molecular formula of CBDP is C23H34O2.
Other examples of homologues include the cannabinoid THCB, which is the butyl homologue of tetrahydrocannabinol (THC, delta-9-THC), or THCH, which is the hexyl homologue of THC.
How is it made?
CBDP is found in the cannabis plant, but only in minute quantities, making direct extraction to meet commercial demand not only costly but also unfeasible. In addition, there are currently no known cannabis strains containing high concentrations of CBDP, which is why it is produced in the laboratory.
Behind the production of CBDP is a chemical reaction called isomerisation. In this reaction, a molecule, ion or fragment of a molecule is converted into an isomer that has a different structure. Specifically, CBDP is produced by isomerisation from CBD isolate, which is the purest form of CBD in the form of crystals with 0% THC content.
Since natural cannabidiol serves as the starting material for production, CBDP carries the designation of a semi-synthetic cannabinoid, just like H4CBD, HHC, HHCP or THCJD.
What are the effects of CBDP?
User experience suggests that it has a stronger effect than CBD and is not psychoactive.
However, at the moment there is a lack of research, so it is impossible to say for sure how it works in the body, what effects it has and its possible therapeutic potential.
Considering a study that suggests that the longer the side chain in cannabinoid compounds, the better the binding to receptors in the endocannabinoid system (ECS) in the body, this could explain why some believe CBDP has a better binding to CB2 receptors than CBD.
However, the aforementioned theory from this study is contradicted by research from Italian scientists, which states that CBDP shows low binding to both CB2 and CB1 receptors.
This means that no conclusions can currently be drawn about how and by what force it acts on the receptors in the ECS.
CBDP appears to exhibit antioxidant, antiepileptic and anti-inflammatory properties.
Italian researchers have recently looked at the potential of CBDP against breast cancer and in a 2021 study suggested that its effects are similar to those of CBD, but apparently more potent and it seems that it could help fight breast cancer cells. It also looks like CBDP could enhance the effect of some cancer drugs already in use. In addition, when CBDP was administered along with CBD, it enhanced each of the above effects.
This could possibly be related to the so-called entourage effect. This phenomenon is characterised by the fact that when cannabinoids and other active substances act together, the effect of the individual components may be enhanced. The additive effect occurs with full spectrum and broad spectrum products.
Although the outcome of research on the potential against breast cancer appears very promising, further research is needed.
Possible side effects
CBD is generally considered a well-tolerated and safe substance. Adverse effects are rare and are mainly at risk at high doses. It can be assumed that similar potential side effects may occur with CBDP, namely:
- tiredness or drowsiness
- dry mouth
- changes in appetite
- change of mood
- Vertigo
- abdominal pain
- diarrhea
These effects usually subside after a short period of time and their intensity will depend on several factors (health, age, body proportions, sensitivity and metabolism of the user, dose and also the method of consumption).
Conclusion
The phytocannabinoid CBDP is found in trace amounts in the cannabis plant. It is produced in the laboratory by a process called isomerisation from a CBD isolate. It is a semi-synthetic cannabinoid that is a heptyl homologue of cannabidiol. Cannabidiol has a 7-carbon side chain, while CBD has a 5-carbon chain.
User experience suggests that it is probably more potent than CBD and that it is not psychotropic. However, at the moment there is a lack of research that thoroughly evaluates how it works in the body overall and what therapeutic potential it may have.
Cannabidiol is legal in the country and you can already try CBDP products, you can get CBDP vape pens and replacement cartridges, which are pre-filled cartridges designed for vaping that combine CBDP and CBD distillate with natural terpenes. Also available are flowers, which are sticks of technical hemp infused with CBDP distillate, tinctures, distillate and hash - a cannabis concentrate made from the flowers of technical hemp.
If you decide to purchase cannabis products, rely on reputable companies that have been in the cannabis market for some time and provide third-party laboratory analysis for their products.
Author: HotHouse Cucumber
Photo: Shutterstock
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